2007

Originalarbeiten

S. Karkola , H.-D. Höltje, K. WähäläA Three-dimensional Model of CYP19 Aromatase Using Rabbit CYP2C5 as a Template. J. Steroid Biochem. Mol. Biol. 105, 63-70, (2007)Birgit Schlegel, Christian Laggner, Rene Meier, Thierry Langer, David Schnell, Roland Seifert, Holger Stark, Hans-Dieter Höltje and Wolfgang SipplGeneration of a homology model of the human histamine H3 receptor for ligand docking and pharmacophore-based screening J. Comput. Aided-Design, 21, 437-53, (2007)Dorothea Jäger, Caroline Schmalenbach, Stefanie Prilla, Jasmin Schrobang, Anna Kebig, Matthias Sennwitz, Eberhard Heller, Christian Tränkle, Ulrike Holzgrabe, Hans-Dieter Höltje und Klaus Mohr Allosteric small moleculares unveil a role of an extracellular E2/TM7 junction for GPCR ActivationJ. Biol.Chem. 282, 34968-76 (2007)M. Rahnasto, C. Wittekindt, R.O. Juvonen, M. Turpeinen, A. Petsalo, O. Pelkonen, A. Poso, G. Stahl, H.-D. Höltje, H. RaunioIdentification of inhibitors of the nicotine metabolising CYP2A6 enzyme - an in silico approach The Pharmacogenomics Journal 8, 328-338 (2007)

Abstracts

G.-Y. Ko, P. Hillmann, C.E. Müller und H.-D. Höltje
Using Molecular Modelling tools to define the putative binding site of a human P2Y₂-receptor model
"Darmstädter Molecular Modelling Workshop"
15.05. -18.05.07, Erlangen

B. Zdrazil, M. Höltje, B. Brandt, M. Schäfer-Korting und H.-D. Höltje
Molecular Dynamics Simulations of new putative human DNA pol a inhibitors for treatmant of excessive kertinocyte proliferation
"Darmstädter Molecular Modelling Workshop"
15.05. -18.05.07, Erlangen