Publikationen (gelistet seit 2017)
| 2025 | |
| Krings, K. S., Ritchie, A., Schmitt, L., Hatzfeld, J., Totzke, G., Lenz, T., Mendiburo, M. J., Stork, B., Teusch, N., Proksch, P., Stuhler, K., Muller, L., & Wesselborg, S. (2025). The Polybrominated Diphenyl Ether Bromoxib Disrupts Nuclear Import and Export by Affecting Nucleoporins of the Nuclear Pore Complex. Mar Drugs, 23(3). doi.org/10.3390/md23030108 | |
| Booker, A., Zabetakis, I., Teusch, N. E., Dalby, A., Hartung, T., & Peter, A. E. (2025). Editorial: Multisystem inflammatory syndrome observed post-COVID-19: the role of natural products, medicinal plants and nutrients and the use of prediction tools supporting traditional forms of diagnosis. Front Pharmacol, 16, 1539793. doi.org/10.3389/fphar.2025.1539793 | |
| Deipenbrock, A., Wilmes, B. E., Sommermann, T., Abdo, N., Moustakas, K., Raasch, M., Rennert, K., & Teusch, N. E. (2025). Modelling of the multicellular tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) on a fit-for-purpose biochip for preclinical drug discovery. Lab Chip. doi.org/10.1039/d4lc01016g | |
| Abba, C. C., Eze, P. M., Ebada, S. S., Eze, N. K., Proksch, P., Teusch, N., Okoye, F. B. C., & Eboka, C. J. (2025). Rare Chlorinated Fungal Metabolite and Alpha-Pyrones from an Endophytic Fungus Nigrospora sp. ACS Omega, 10(6), 5722-5729. doi.org/10.1021/acsomega.4c09190 | |
| 2024 | |
Pharmacological Effects of Paeonia lactiflora Focusing on Painful Diabetic Neuropathy Targeting mitochondrial metabolism by the mitotoxin bromoxib in leukemia and lymphoma cells Novel Histone Deacetylase (HDAC) Inhibitor Induces Apoptosis and Suppresses Invasion via E-Cadherin Upregulation in Pancreatic Ductal Adenocarcinoma (PDAC) Aplospojaveedins A-C, unusual sulfur-containing alkaloids produced by the endophytic fungus Aplosporella javeedii using OSMAC strategy Incorporating immune cell surrogates into a full-thickness tissue equivalent of human skin to characterize dendritic cell activation | |
| 2023 | |
| Indole Diketopiperazine Alkaloids from the Marine Sediment-Derived Fungus Aspergillus chevalieri against Pancreatic Ductal Adenocarcinoma El-Kashef DH, Obidake DD, Schiedlauske K, Deipenbrock A, Scharf S, Wang H, Naumann D, Friedrich D, Miljanovic S, Haj Hassani Sohi T, Janiak C, Pfeffer K, Teusch N. (2023) Marine Drugs, 22, 5. DOI: https://doi.org/10.3390/md22010005 | |
| A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation Hölken JM, Friedrich K, Merkel M, Blasius N, Engels U, Buhl T, Mewes KR, Vierkotten L, Teusch NE. (2023). Frontiers in Immunology, 14. DOI: 10.3389/fimmu.2023.1276151 | |
| The Monocytic Cell Line THP-1 as a Validated and Robust Surrogate Model for Human Dendritic Cells Hölken JM, Teusch N. (2023) International Journal of Molecular Sciences; 24(2):1452. DOI: https://doi.org/10.3390/ijms24021452 | |
| 2022 | |
| Uysal, K., Creutz, T., Firat, I. S., Artmann, G. M., Teusch, N., & Temiz Artmann, A. (2022). Bio-Functionalized Ultra-Thin, Large-Area and Waterproof Silicone Membranes for Biomechanical Cellular Loading and Compliance Experiments. Polymers (Basel), 14(11). doi.org/10.3390/polym14112213 | |
| Uysal, K., Firat, I. S., Creutz, T., Aydin, I. C., Artmann, G. M., Teusch, N., & Temiz Artmann, A. (2022). A Novel In Vitro Wound Healing Assay Using Free-Standing, Ultra-Thin PDMS Membranes. Membranes (Basel), 13(1). doi.org/10.3390/membranes13010022 | |
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism. Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer | |
| Total Synthesis of (+)‐Erogorgiaene and the Pseudopterosin A−F Aglycone via Enantioselective Cobalt‐Catalyzed Hydrovinylation Movahhed S, Westphal J, Kempa A, Schumacher C E, Sperlich J, Neudörfl J-M, Teusch N, Hochgürtel M, Schmalz H-G. (2022), Chemistry – A European Journal 27(45): 11574–11579, DOI: 10.1002/chem.202101863 | |
| 2021 | |
| El-Kashef, D. H., Youssef, F. S., Reimche, I., Teusch, N., Muller, W. E. G., Lin, W., Frank, M., Liu, Z., & Proksch, P. (2021). Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies. Bioorg Med Chem, 29, 115883. doi.org/10.1016/j.bmc.2020.115883 | |
| Movahhed, S., Westphal, J., Kempa, A., Schumacher, C. E., Sperlich, J., Neudorfl, J. M., Teusch, N., Hochgurtel, M., & Schmalz, H. G. (2021). Total Synthesis of (+)-Erogorgiaene and the Pseudopterosin A-F Aglycone via Enantioselective Cobalt-Catalyzed Hydrovinylation. Chemistry, 27(45), 11574-11579. doi.org/10.1002/chem.202101863 | |
| Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies El-Kashef DH, Youssef FS, Reimche I, Teusch N, Müller WEG, Lin W, Frank M, Liu Z, Proksch P. (2021) Bioorg Med Chem., Jan 1 (29): 115883, DOI: 10.1016/j.bmc.2020.115883 | |
| 2020 | |
| Ariantari, N. P., Ancheeva, E., Frank, M., Stuhldreier, F., Meier, D., Groner, Y., Reimche, I., Teusch, N., Wesselborg, S., Muller, W. E. G., Kalscheuer, R., Liu, Z., & Proksch, P. (2020). Didymellanosine, a new decahydrofluorene analogue, and ascolactone C from Didymella sp. IEA-3B.1, an endophyte of Terminalia catappa. RSC Adv, 10(12), 7232-7240. doi.org/10.1039/c9ra10685e | |
| Pseudopterosin and tylophorinine suppress cell growth in 3D spheroid co-culture models of pancreatic ductal adenocarcinoma Xie B, Hänsel J, Mundorf V, Betz J, Reimche I, Erkan M, Büdeyri I, Barlas T, Gesell A, De Bank P, Mrsny R, Teusch N. (2020), Bioengineering 7 (2): 57, DOI: 10.3390/bioengineering7020057 | |
| Recent developments of 3D models of the tumor microenvironment for cutaneous melanoma: Bridging the gap between the bench and the bedside? Hölken J M, Teusch N. (2020) Journal of Translational Science 7: 1-7, DOI: 10.15761/JTS.1000388 | |
| The Birch Bracket Medicinal Mushroom, Fomitopsis betulina (Agaricomycetes) - Bioactive Source for Beta-Glucan Fraction with Tumor Cell Migration Blocking Ability Sari M, Toepler K, Roth C, Teusch N, Hambitzer R. (2020) Int J Med Mushrooms, 22(1): 1-13, DOI:10.1615/IntJMedMushrooms.2019033291 | |
| Azaphilones from the Red Sea Fungus Aspergillus falconensis El-Kashef DH, Youssef FS, Hartmann R, Knedel TO, Janiak C, Lin W, Reimche I, Teusch N, Liu Z, Proksch P. (2020), Marine Drugs, 18(4): 204, DOI: 10.3390/md18040204 | |
| Comparison of two-and three-dimensional cancer models for assessing potential cancer therapeutics Xie B, Teusch N, Mrsny R. (2020) Biomaterials for Cancer Therapeutics 2: 399-423, DOI: 10.1016/B978-0-08-102983-1.00014-4 | |
| 2019 | |
| Nolte, J., Pottgen, L. A., Sperlich, J., Grossert, A., Kempa, A., Teusch, N., & Schorken, U. (2019). Glucansucrase catalyzed synthesis and functional characterization of nordihydroguaiaretic acid glucosides. Enzyme Microb Technol, 120, 69-76. doi.org/10.1016/j.enzmictec.2018.10.002 | |
| Sachs, J., Kadioglu, O., Weber, A., Mundorf, V., Betz, J., Efferth, T., Pietruszka, J., & Teusch, N. (2019). Selective inhibition of P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy. J Nat Med, 73(1), 226-235. doi.org/10.1007/s11418-018-1230-x | |
| Ketamine increases proliferation of human iPSC-derived neuronal progenitor cells via insulin-like growth factor 2 and indepenpendent of the NMDA receptor Grossert A, Mehrjardi NZ, Bailey SJ, Lindsay MA, Hescheler J, Saric T, Teusch N. (2019), Cells 8: 1139, DOI: 10.3390/cells8101139 | |
| Azaphilone pigments and macrodiolides from the coprophilous fungus Coniella fragariae Yu H, Sperlich J, Hofert SP, Janiak C, Teusch N, Stuhldreier F, Wesselborg S, Wang C, Kassack MU, Dai H, Liu Z, Proksch P. (2019), Fitoterapia 137: 104249, DOI: 10.1016/j.fitote.2019.104249 | |
| Novel 3,4-dihydroisocoumarines inhibit human P-gp and BCRP in multidrug resistant tumors and demonstrate substrate inhibition of yeast Pdr5 Sachs J, Döhl K, Weber A, Bonus M, Gohlke H, Pietruszka J, Schmitt L, Teusch N. (2019), Frontiers in Pharmacology 10 (400), DOI: 10.3389/fphar.2019.00400 | |
| 2018 | |
| Sari, M., Toepler, K., Nickisch-Hartfiel, A., Teusch, N., & Hambitzer, R. (2018). Cross-Flow Ultrafiltration Fractions of a Cold Aqueous Extract of the Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Exhibit Apoptosis in Tumor Cells. Int J Med Mushrooms, 20(11), 1107-11119. doi.org/10.1615/IntJMedMushrooms.2018028980 | |
| Pseudopterosin inhibits proliferation and 3D invasion in triple-negative breast cancer by agonizing glucocorticoid receptor alpha Sperlich J & Teusch N. (2018), Molecules 23(8): 1992, DOI: 10.3390/molecules23081992 | |
| Selective inhibition of the P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy Sachs J, Kadioglu O, Weber A, Mundorf V, Betz J, Efferth T, Pietruszka J, Teusch N. (2018), Journal of Natural Medicines 73(1): 226-235, DOI: 10.1007/s11418-018-1230-x | |
| Synthetic indolactam V analogs as inhibitors of PAR2 induced calcium mobilization in triple negative breast cancer cells Stein J, Stahn S, Neudörfl JM, Sperlich J, Schmalz HG, Teusch N. (2018), ChemMedChem 13(2): 147-154, DOI: 10.1002/cmdc.201700640 | |
| Azaphilone derivatives from the dung-inhabiting fungus Coniella fragariae inhibit NF-κB activation and reduce tumor cell migration Yu H, Sperlich J, Mándi A, Kurtán T, Dai H, Teusch N, Guo ZY, Zou K, Liu Z, Proksch P. (2018), Journal of Natural Products 81: 2493-2500, DOI: 10.1021/acs.jnatprod.8b00540 | |
| 2017 | |
| The marine natural product pseudopterosin blocks cytokine release of triple-negative breast cancer and monocytic leukemia cells by inhibiting NF-κB signaling Sperlich J, Kerr R, Teusch N. (2017), Marine Drugs 15(9): 262-276, DOI: 10.3390/md15090262 | |
| Synthesis and cytotoxic activities of goniothalamins and derivatives Weber A, Döhl K, Sachs J, Nordschild AC, Schröder D, Kulik A, Fischer T, Schmitt L, Teusch N, Pietruszka J. (2017) Biorg. Med. Chem. 6(16): 31101-4, DOI: 10.1016/j.bmc.2017.02.004 |