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Publikationen (gelistet seit 2017)

2025 
 Krings, K. S., Ritchie, A., Schmitt, L., Hatzfeld, J., Totzke, G., Lenz, T., Mendiburo, M. J., Stork, B., Teusch, N., Proksch, P., Stuhler, K., Muller, L., & Wesselborg, S. (2025). The Polybrominated Diphenyl Ether Bromoxib Disrupts Nuclear Import and Export by Affecting Nucleoporins of the Nuclear Pore Complex. Mar Drugs, 23(3). doi.org/10.3390/md23030108 
 Booker, A., Zabetakis, I., Teusch, N. E., Dalby, A., Hartung, T., & Peter, A. E. (2025). Editorial: Multisystem inflammatory syndrome observed post-COVID-19: the role of natural products, medicinal plants and nutrients and the use of prediction tools supporting traditional forms of diagnosis. Front Pharmacol, 16, 1539793. doi.org/10.3389/fphar.2025.1539793 
 Deipenbrock, A., Wilmes, B. E., Sommermann, T., Abdo, N., Moustakas, K., Raasch, M., Rennert, K., & Teusch, N. E. (2025). Modelling of the multicellular tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) on a fit-for-purpose biochip for preclinical drug discovery. Lab Chip. doi.org/10.1039/d4lc01016g 
 Abba, C. C., Eze, P. M., Ebada, S. S., Eze, N. K., Proksch, P., Teusch, N., Okoye, F. B. C., & Eboka, C. J. (2025). Rare Chlorinated Fungal Metabolite and Alpha-Pyrones from an Endophytic Fungus Nigrospora sp. ACS Omega, 10(6), 5722-5729. doi.org/10.1021/acsomega.4c09190 
2024 
 

Pharmacological Effects of Paeonia lactiflora Focusing on Painful Diabetic Neuropathy
Wiegand, V., Gao, Y., & Teusch, N. (2024). Planta Med, 90(15), 1115-1129. doi.org/10.1055/a-2441-6488

Targeting mitochondrial metabolism by the mitotoxin bromoxib in leukemia and lymphoma cells
Schmitt, L., Krings, K. S., Wolsing, A., Buque, X., Zimmermann, M., Flores-Romero, H., Lenz, T., Lechtenberg, I., Peter, C., Stork, B., Teusch, N., Proksch, P., Stuhler, K., Garcia-Saez, A. J., Reichert, A. S., Aspichueta, P., Bhatia, S., & Wesselborg, S. (2024). Cell Commun Signal, 22(1), 541. doi.org/10.1186/s12964-024-01913-2

Novel Histone Deacetylase (HDAC) Inhibitor Induces Apoptosis and Suppresses Invasion via E-Cadherin Upregulation in Pancreatic Ductal Adenocarcinoma (PDAC)
Schiedlauske, K., Deipenbrock, A., Pflieger, M., Hamacher, A., Hansel, J., Kassack, M. U., Kurz, T., & Teusch, N. E. (2024).  Pharmaceuticals (Basel), 17(6). doi.org/10.3390/ph17060752

Aplospojaveedins A-C, unusual sulfur-containing alkaloids produced by the endophytic fungus Aplosporella javeedii using OSMAC strategy
Gao, Y., Frank, M., Teusch, N., Woschko, D., Janiak, C., Mandi, A., Kurtan, T., Hartmann, R., Schiedlauske, K., van Geelen, L., Kalscheuer, R., Kaiser, J., Gertzen, C. G. W., Gohlke, H., Wang, B. G., Proksch, P., & Liu, Z. (2024).  Front Microbiol, 15, 1458622. doi.org/10.3389/fmicb.2024.1458622

Incorporating immune cell surrogates into a full-thickness tissue equivalent of human skin to characterize dendritic cell activation
Holken, J. M., Wurz, A. L., Friedrich, K., Bottcher, P., Asskali, D., Stark, H., Breitkreutz, J., Buhl, T., Vierkotten, L., Mewes, K. R., & Teusch, N. (2024).  Sci Rep, 14(1), 30158. doi.org/10.1038/s41598-024-81014-9 

2023 
 Indole Diketopiperazine Alkaloids from the Marine Sediment-Derived Fungus Aspergillus chevalieri against Pancreatic Ductal Adenocarcinoma
El-Kashef DH, Obidake DD, Schiedlauske K, Deipenbrock A, Scharf S, Wang H, Naumann D, Friedrich D, Miljanovic S, Haj Hassani Sohi T, Janiak C, Pfeffer K, Teusch N. (2023)  Marine Drugs, 22, 5. DOI:  https://doi.org/10.3390/md22010005
 A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation
Hölken JM, Friedrich K, Merkel M, Blasius N, Engels U, Buhl T, Mewes KR, Vierkotten L, Teusch NE. (2023). Frontiers in Immunology, 14. DOI: 10.3389/fimmu.2023.1276151
 The Monocytic Cell Line THP-1 as a Validated and Robust Surrogate Model for Human Dendritic Cells
Hölken JM, Teusch N. (2023) International Journal of Molecular Sciences; 24(2):1452. DOI: https://doi.org/10.3390/ijms24021452
2022 
 Uysal, K., Creutz, T., Firat, I. S., Artmann, G. M., Teusch, N., & Temiz Artmann, A. (2022). Bio-Functionalized Ultra-Thin, Large-Area and Waterproof Silicone Membranes for Biomechanical Cellular Loading and Compliance Experiments. Polymers (Basel), 14(11). doi.org/10.3390/polym14112213 
 Uysal, K., Firat, I. S., Creutz, T., Aydin, I. C., Artmann, G. M., Teusch, N., & Temiz Artmann, A. (2022). A Novel In Vitro Wound Healing Assay Using Free-Standing, Ultra-Thin PDMS Membranes. Membranes (Basel), 13(1). doi.org/10.3390/membranes13010022 
 

The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism.
Stuhldreier F, Schmitt L, Lenz T, et al. (2022) Cell Death Dis.;13(11):938. doi:10.1038/s41419-022-05356-w

Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer
Reimche I, Yu H, Ariantari NP, Liu Z, Merkens K, Rotfuß S, Peter K, Jungwirth U, Bauer N, Kiefer D, Neudörfl J-M, Schmalz H-G, Proksch P, Teusch N. (2022) International Journal of Molecular Science 23 (18): 10319, DOI: 10.3390/ijms231810319

 Total Synthesis of (+)‐Erogorgiaene and the Pseudopterosin A−F Aglycone via Enantioselective Cobalt‐Catalyzed Hydrovinylation
Movahhed S, Westphal J, Kempa A, Schumacher C E, Sperlich J, Neudörfl J-M, Teusch N, Hochgürtel M, Schmalz H-G. (2022), Chemistry – A European Journal 27(45): 11574–11579, DOI: 10.1002/chem.202101863
2021 
 El-Kashef, D. H., Youssef, F. S., Reimche, I., Teusch, N., Muller, W. E. G., Lin, W., Frank, M., Liu, Z., & Proksch, P. (2021). Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies. Bioorg Med Chem, 29, 115883. doi.org/10.1016/j.bmc.2020.115883 
 Movahhed, S., Westphal, J., Kempa, A., Schumacher, C. E., Sperlich, J., Neudorfl, J. M., Teusch, N., Hochgurtel, M., & Schmalz, H. G. (2021). Total Synthesis of (+)-Erogorgiaene and the Pseudopterosin A-F Aglycone via Enantioselective Cobalt-Catalyzed Hydrovinylation. Chemistry, 27(45), 11574-11579. doi.org/10.1002/chem.202101863 
 Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies 
El-Kashef DH, Youssef FS, Reimche I, Teusch N, Müller WEG, Lin W, Frank M, Liu Z, Proksch P. (2021) Bioorg Med Chem., Jan 1 (29): 115883, DOI: 10.1016/j.bmc.2020.115883
2020 
 Ariantari, N. P., Ancheeva, E., Frank, M., Stuhldreier, F., Meier, D., Groner, Y., Reimche, I., Teusch, N., Wesselborg, S., Muller, W. E. G., Kalscheuer, R., Liu, Z., & Proksch, P. (2020). Didymellanosine, a new decahydrofluorene analogue, and ascolactone C from Didymella sp. IEA-3B.1, an endophyte of Terminalia catappa. RSC Adv, 10(12), 7232-7240. doi.org/10.1039/c9ra10685e
 Pseudopterosin and tylophorinine suppress cell growth in 3D spheroid co-culture models of pancreatic ductal adenocarcinoma 
Xie B, Hänsel J, Mundorf V, Betz J, Reimche I, Erkan M, Büdeyri I, Barlas T, Gesell A, De Bank P, Mrsny R, Teusch N. (2020), Bioengineering 7 (2): 57, DOI: 10.3390/bioengineering7020057
 Recent developments of 3D models of the tumor microenvironment for cutaneous melanoma: Bridging the gap between the bench and the bedside? 
Hölken J M, Teusch N. (2020) Journal of Translational Science 7: 1-7, DOI: 10.15761/JTS.1000388
 The Birch Bracket Medicinal Mushroom, Fomitopsis betulina (Agaricomycetes) - Bioactive Source for Beta-Glucan Fraction with Tumor Cell Migration Blocking Ability
Sari M, Toepler K, Roth C, Teusch N, Hambitzer R. (2020) Int J Med Mushrooms, 22(1): 1-13, DOI:10.1615/IntJMedMushrooms.2019033291
 Azaphilones from the Red Sea Fungus Aspergillus falconensis
El-Kashef DH, Youssef FS, Hartmann R, Knedel TO, Janiak C, Lin W, Reimche I, Teusch N, Liu Z, Proksch P. (2020), Marine Drugs, 18(4): 204, DOI: 10.3390/md18040204
 Comparison of two-and three-dimensional cancer models for assessing potential cancer therapeutics
Xie B, Teusch N, Mrsny R. (2020) Biomaterials for Cancer Therapeutics 2: 399-423, DOI: 10.1016/B978-0-08-102983-1.00014-4
2019 
 Nolte, J., Pottgen, L. A., Sperlich, J., Grossert, A., Kempa, A., Teusch, N., & Schorken, U. (2019). Glucansucrase catalyzed synthesis and functional characterization of nordihydroguaiaretic acid glucosides. Enzyme Microb Technol, 120, 69-76. doi.org/10.1016/j.enzmictec.2018.10.002 
 Sachs, J., Kadioglu, O., Weber, A., Mundorf, V., Betz, J., Efferth, T., Pietruszka, J., & Teusch, N. (2019). Selective inhibition of P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy. J Nat Med, 73(1), 226-235. doi.org/10.1007/s11418-018-1230-x 
 Ketamine increases proliferation of human iPSC-derived neuronal progenitor cells via insulin-like growth factor 2 and indepenpendent of the NMDA receptor 
Grossert A, Mehrjardi NZ, Bailey SJ, Lindsay MA, Hescheler J, Saric T, Teusch N. (2019), Cells 8: 1139, DOI: 10.3390/cells8101139
 Azaphilone pigments and macrodiolides from the coprophilous fungus Coniella fragariae
Yu H, Sperlich J, Hofert SP, Janiak C, Teusch N, Stuhldreier F, Wesselborg S, Wang C, Kassack MU, Dai H, Liu Z, Proksch P. (2019), Fitoterapia 137: 104249, DOI: 10.1016/j.fitote.2019.104249
 Novel 3,4-dihydroisocoumarines inhibit human P-gp and BCRP in multidrug resistant tumors and demonstrate substrate inhibition of yeast Pdr5
Sachs J, Döhl K, Weber A, Bonus M, Gohlke H, Pietruszka J, Schmitt L, Teusch N. (2019), Frontiers in Pharmacology 10 (400), DOI: 10.3389/fphar.2019.00400
2018 
 Sari, M., Toepler, K., Nickisch-Hartfiel, A., Teusch, N., & Hambitzer, R. (2018). Cross-Flow Ultrafiltration Fractions of a Cold Aqueous Extract of the Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Exhibit Apoptosis in Tumor Cells. Int J Med Mushrooms, 20(11), 1107-11119. doi.org/10.1615/IntJMedMushrooms.2018028980 
 Pseudopterosin inhibits proliferation and 3D invasion in triple-negative breast cancer by agonizing glucocorticoid receptor alpha
Sperlich J & Teusch N. (2018), Molecules 23(8): 1992, DOI: 10.3390/molecules23081992
 Selective inhibition of the P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy
Sachs J, Kadioglu O, Weber A, Mundorf V, Betz J, Efferth T, Pietruszka J, Teusch N. (2018), Journal of Natural Medicines 73(1): 226-235, DOI: 10.1007/s11418-018-1230-x
 Synthetic indolactam V analogs as inhibitors of PAR2 induced calcium mobilization in triple negative breast cancer cells
Stein J, Stahn S, Neudörfl JM, Sperlich J, Schmalz HG, Teusch N. (2018), ChemMedChem 13(2): 147-154, DOI: 10.1002/cmdc.201700640
 Azaphilone derivatives from the dung-inhabiting fungus Coniella fragariae inhibit NF-κB activation and reduce tumor cell migration
Yu H, Sperlich J, Mándi A, Kurtán T, Dai H, Teusch N, Guo ZY, Zou K, Liu Z, Proksch P. (2018), Journal of Natural Products 81: 2493-2500, DOI: 10.1021/acs.jnatprod.8b00540
2017 
 The marine natural product pseudopterosin blocks cytokine release of triple-negative breast cancer and monocytic leukemia cells by inhibiting NF-κB signaling
Sperlich J, Kerr R, Teusch N. (2017), Marine Drugs 15(9): 262-276, DOI: 10.3390/md15090262
 Synthesis and cytotoxic activities of goniothalamins and derivatives
Weber A, Döhl K, Sachs J, Nordschild AC, Schröder D, Kulik A, Fischer T, Schmitt L, Teusch N, Pietruszka J. (2017) Biorg. Med. Chem. 6(16): 31101-4, DOI: 10.1016/j.bmc.2017.02.004