Selected Publications

2024

2023
	Indole Diketopiperazine Alkaloids from the Marine Sediment-Derived Fungus Aspergillus chevalieri against Pancreatic Ductal Adenocarcinoma El-Kashef DH, Obidake DD, Schiedlauske K, Deipenbrock A, Scharf S, Wang H, Naumann D, Friedrich D, Miljanovic S, Haj Hassani Sohi T, Janiak C, Pfeffer K, Teusch N, 2023, Marine Drugs, 22, 5. DOI: https://doi.org/10.3390/md22010005
	A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation Hölken, JM, Friedrich K, Merkel M, Blasius N, Engels U, Buhl T, Mewes KR, Vierkotten L, Teusch NE, 2023, Frontiers in Immunology, 14. DOI: 10.3389/fimmu.2023.1276151
	The Monocytic Cell Line THP-1 as a Validated and Robust Surrogate Model for Human Dendritic Cells Hölken JM, Teusch N, 2023, International Journal of Molecular Sciences; 24(2):1452. DOI: https://doi.org/10.3390/ijms24021452
2022
	Phenanthroindolizidine Alkaloids Isolated from Tylophora ovata as Potent Inhibitors of Inflammation, Spheroid Growth, and Invasion of Triple-Negative Breast Cancer Reimche I, Yu H, Ariantari NP, Liu Z, Merkens K, Rotfuß S, Peter K, Jungwirth U, Bauer N, Kiefer D, Neudörfl J-M, Schmalz H-G, Proksch P, Teusch N, 2022, International Journal of Molecular Science 23 (18): 10319, DOI: 10.3390/ijms231810319
	Total Synthesis of (+)‐Erogorgiaene and the Pseudopterosin A−F Aglycone via Enantioselective Cobalt‐Catalyzed Hydrovinylation Movahhed S, Westphal J, Kempa A, Schumacher C E, Sperlich J, Neudörfl J-M, Teusch N, Hochgürtel M, Schmalz H-G, 2022, *Chemistry – A European Journal* 27(45): 11574–11579, DOI: 10.1002/chem.202101863
2021
	Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies El-Kashef DH, Youssef FS, Reimche I, Teusch N, Müller WEG, Lin W, Frank M, Liu Z, Proksch P. 2021 *Bioorg Med Chem.*, Jan 1 (29): 115883, DOI: 10.1016/j.bmc.2020.115883
2020
	Pseudopterosin and tylophorinine suppress cell growth in 3D spheroid co-culture models of pancreatic ductal adenocarcinoma Xie B, Hänsel J, Mundorf V, Betz J, Reimche I, Erkan M, Büdeyri I, Barlas T, Gesell A, De Bank P, Mrsny R, Teusch N, 2020, *Bioengineering* 7 (2): 57, DOI: 10.3390/bioengineering7020057
	Recent developments of 3D models of the tumor microenvironment for cutaneous melanoma: Bridging the gap between the bench and the bedside? Hölken J M, Teusch N, 2020, Journal of Translational Science 7: 1-7, DOI: 10.15761/JTS.1000388
	The Birch Bracket Medicinal Mushroom, Fomitopsis betulina (Agaricomycetes) - Bioactive Source for Beta-Glucan Fraction with Tumor Cell Migration Blocking Ability Sari M, Toepler K, Roth C, Teusch N, Hambitzer R. 2020, *Int J Med Mushrooms*, 22(1): 1-13, DOI:10.1615/IntJMedMushrooms.2019033291
	Azaphilones from the Red Sea Fungus Aspergillus falconensis El-Kashef DH, Youssef FS, Hartmann R, Knedel TO, Janiak C, Lin W, Reimche I, Teusch N, Liu Z, Proksch P. 2020, *Marine Drugs*, 18(4): 204, DOI: 10.3390/md18040204
	Comparison of two-and three-dimensional cancer models for assessing potential cancer therapeutics Xie B, Teusch N, Mrsny R, 2020, *Biomaterials for Cancer Therapeutics* 2: 399-423, DOI: 10.1016/B978-0-08-102983-1.00014-4
2019
	Ketamine increases proliferation of human iPSC-derived neuronal progenitor cells via insulin-like growth factor 2 and indepenpendent of the NMDA receptor Grossert A, Mehrjardi NZ, Bailey SJ, Lindsay MA, Hescheler J, Saric T, Teusch N, 2019, *Cells* 8: 1139, DOI: 10.3390/cells8101139
	Azaphilone pigments and macrodiolides from the coprophilous fungus Coniella fragariae Yu H, Sperlich J, Hofert SP, Janiak C, Teusch N, Stuhldreier F, Wesselborg S, Wang C, Kassack MU, Dai H, Liu Z, Proksch P, 2019, Fitoterapia 137: 104249, DOI: 10.1016/j.fitote.2019.104249
	Novel 3,4-dihydroisocoumarines inhibit human P-gp and BCRP in multidrug resistant tumors and demonstrate substrate inhibition of yeast Pdr5 Sachs J, Döhl K, Weber A, Bonus M, Gohlke H, Pietruszka J, Schmitt L, Teusch N, 2019, Frontiers in Pharmacology 10 (400), DOI: 10.3389/fphar.2019.00400
2018
	Pseudopterosin inhibits proliferation and 3D invasion in triple-negative breast cancer by agonizing glucocorticoid receptor alpha Sperlich J & Teusch N, 2018, *Molecules* 23(8): 1992, DOI: 10.3390/molecules23081992
	Selective inhibition of the P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy Sachs J, Kadioglu O, Weber A, Mundorf V, Betz J, Efferth T, Pietruszka J, Teusch N, 2018, *Journal of Natural Medicines* 73(1): 226-235, DOI: 10.1007/s11418-018-1230-x
	Synthetic indolactam V analogs as inhibitors of PAR2 induced calcium mobilization in triple negative breast cancer cells Stein J, Stahn S, Neudörfl JM, Sperlich J, Schmalz HG, Teusch N, 2018, *ChemMedChem* 13(2): 147-154, DOI: 10.1002/cmdc.201700640
	Azaphilone derivatives from the dung-inhabiting fungus Coniella fragariae inhibit NF-κB activation and reduce tumor cell migration Yu H, Sperlich J, Mándi A, Kurtán T, Dai H, Teusch N, Guo ZY, Zou K, Liu Z, Proksch P, 2018, *Journal of Natural Products* 81: 2493-2500, DOI: 10.1021/acs.jnatprod.8b00540
2017
	The marine natural product pseudopterosin blocks cytokine release of triple-negative breast cancer and monocytic leukemia cells by inhibiting NF-κB signaling Sperlich J, Kerr R, Teusch N, 2017, *Marine Drugs* 15(9): 262-276, DOI: 10.3390/md15090262
	Synthesis and cytotoxic activities of goniothalamins and derivatives Weber A, Döhl K, Sachs J, Nordschild AC, Schröder D, Kulik A, Fischer T, Schmitt L, Teusch N, Pietruszka J, 2017, *Biorg. Med. Chem.* 6(16): 31101-4, DOI: 10.1016/j.bmc.2017.02.004

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